Omics and computational study of exosomes to identify pathways, biomarkers and mediators of inflammation

MetaMilk is an innovative research partnership with enormous benefits for health, science, and society. A detailed and extensive analysis of the composition of milk-derived extracellular vesicles, and other microparticles and milk components from four taxonomical species, including humans as a reference species, is proposed. Access to large medical and omic-based data related to milk, milk-exosomes and lactation endocrinology will drive a thorough bioinformatics and computational analysis based on transcriptomic, proteomic and metabolomic data in conjunction with the use and integration of comparative phylogenetic analysis data. Species-specific or conserved within animal milk molecular networks, relative to human milk and inflammatory pathways, are expected to be revealed.