Module 1: Pharmacokinetics and pharmacodynamics
1) Terms and models of pharmacokinetics and pharmacodynamics
2) Dose-response curves
3) Drug-receptor interactions and quantitative aspects
4) Pharmacodynamics mechanisms and classification
5) Drug metabolism and excretion
Module 2: Clinical biotechnology
1) Basic modules of clinical (bio)chemistry/biotechnology.
2) Pathobiochemistry and importance of enzymes, hormones and molecular markers.
3) Post-translational modifications and therapeutic proteins.
4) Molecular biology of cancer and drug design.
5) Cytokines and protein immunogenicity.
6) Growth factors and their application as therapeutics.
Module 3: Pharmaceutical Biotechnology
1) Principles of pharmaceutical biotechnology
2) Principles for development, production, formulation and delivery of biological molecules as drugs
3) Protein-engineering of therapeutic proteins
4) Properties and applications of proteins and vaccines as therapeutic biotechnological products
5) Design of recombinant hormones with therapeutic use
Module 4: Gene therapy, pharmacogenomics and bioethics
1) Gene therapy and stem-cell technology
2) Pharmacogenomics and pharmacoproteomics
3) Polymorphisms (SNPs) of drug targets and pharmacodynamics
4) Bioethics-what a scientist should be thinking
5) Intellectual property in pharmaceutical biotechnology
1). PRINCIPLES OF CLINICAL CHEMISTRY AND MOLECULAR DIAGNOSTICS, Α. Skorilas (author),
Symmeria Publications - Μ. Αthanasopoulos - S. Αthanasopoulos Ο.Ε., Athens 2009.
(ISBN: 978-960-266-271-7).
2). CLINICAL BIOCHEMISTRY: METABOLIC AND CLINICAL ASPECTS, W.J. Marshall (author),
Churchill Livingstone, 3
rd edition, 2014
(ISBN: 978-0-7020-5140-1).
3). PHARMACEUTICAL BIOTECHNOLOGY: CONCEPTS & APPLICATIONS, G. Walsh (συγγραφέας)
Wiley Publishing Co., 2007, (ISBN: 978-0-470-01244-4)
