{"id":793,"date":"2023-05-16T10:48:29","date_gmt":"2023-05-16T10:48:29","guid":{"rendered":"https:\/\/w1.aua.gr\/etda\/?post_type=courses&#038;p=793"},"modified":"2024-06-20T14:14:22","modified_gmt":"2024-06-20T14:14:22","slug":"genetics","status":"publish","type":"courses","link":"https:\/\/w1.aua.gr\/etda\/en\/courses\/genetics\/","title":{"rendered":"Genetics"},"content":{"rendered":"\n<p>This is a basic course that presents the fundamentals of the science of Genetics.<br>Its aim is to introduce students to the basic principles of Genetics, while also reporting to the theory and techniques of genetic analysis.<br>Lastly, the course\u2019s aim is the understanding of the methodology of solving Genetics problems.<br>After successfully completing this course, students will:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Have acquired knowledge on the functions and interactions of genes<\/li>\n\n\n\n<li>Have acquired competencies in the techniques of Mendelian analysis<\/li>\n\n\n\n<li>Be able to interpret the outcomes of crosses between monohybrids, dihybrids and multihybrids and define in detail the genotypes and phenotypes of all individuals.<\/li>\n\n\n\n<li>Be able to calculate \u03c72 to decide whether observations of progenies ratios in particular crosses deviate from expectations purely on the basis of chance.<\/li>\n\n\n\n<li>Be able to explain the results of dihybrid crosses and define in full detail the genotype and phenotype of all individuals intergenerational and intragenerational.<\/li>\n\n\n\n<li>Be able to test experimental results in dihybrids crosses under different regimes of dominance and epistasis and use the \u03c72 test to reject or not a precise null hypothesis.<\/li>\n\n\n\n<li>Have become familiar with the ways in which the environment affects the manifestation of the phenotype, the norm of reaction of a genotype, genotype-environment interactions, twin studies, and their applications.<\/li>\n\n\n\n<li>Be able to calculate the estimated distance between linked genes based on outcomes for crosses involving these genes.<\/li>\n\n\n\n<li>Be able to explain the outcomes of crosses between dihybrids for linked genes and define in detail the genotypic and phenotypic ratios of progenies in all generations.<\/li>\n\n\n\n<li>Be able to perform a three \u2013 point testcross and draw a linkage map of the linked \u2013 genes, showing the order and the distance in map units.<\/li>\n\n\n\n<li>Have familiarized themselves with the cell cycle, mitosis, meiosis.<\/li>\n\n\n\n<li>Understand the mechanisms of sex determination in animals.<\/li>\n\n\n\n<li>Learn about the structure of \u03a5 chromosome and understand the importance of the SRY gene in the development of testis in mammals, while also interpret what causes sex reversal.<\/li>\n\n\n\n<li>Learn about the structure of X chromosome and understand the importance of X-inactivation for the dose compensation through epigenetic mechanisms.<\/li>\n\n\n\n<li>Understand the sex-linked inheritance and distinguish it from sex-influenced and sex-limited inheritance.<\/li>\n\n\n\n<li>Learn about the types of gene mutations, how they are caused, and interpret their effects in protein structure and function as well as in diseases.<\/li>\n\n\n\n<li>Know the types of chromosome mutations, such as deletions, duplications, inversions, translocations, and understand how they develop and their effect in individuals and their gametes.<\/li>\n\n\n\n<li>Have understood how to use plant monosomic lines for a gene and, through appropriate crosses, identify the chromosome that carries the gene.<\/li>\n\n\n\n<li>Have gained knowledge about extra-nuclear inheritance, the theory of endosymbiosis, the molecular genetics of mitochondria and chloroplasts, and human diseases associated with mutations in mitochondrial DNA<\/li>\n\n\n\n<li>Have developed their ability to collaborate with other students to solve complex Genetics problems.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>This is a basic course that presents the fundamentals of the science of Genetics.Its 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